Program

Lessons from RKIP: Rewiring Signaling Pathways as a Therapeutic Approach to Cancer

Marsha Rosner

RKIP – a regulator of beta-adrenergic signaling in the heart

Kristina Lorenz

RKIP as a CDK1-regulated inhibitor of the mitotic checkpoint

Christopher Figy

To be confirmed: Presenter not on the invited speaker list.

Discussion

Coffee break / poster session

Phase separation regulates YY1-mediated enhancer formation in cancer cells

Guangchao Sui

Balance of Yin Yang Family and Regulation of Cellular Redox Homeostasis

Vivi Kasim

The importance of structural disorder in the molecular recognition of YY1 partners

Andrzej Górecki

To be confirmed: Brief lists this time as “12:20 am”; shown as pm pending confirmation.

Discussion

To be confirmed: Brief lists this time as “12:45 am”.

Light lunch

Effect of RKIP loss in mammary duct development and neoplastic transformation

Kam Yeung

Synthetic biological investigation of the RKIP-BACH1 regulatory network

Gábor Balázsi

Usefulness of RKIP assessment in various cancer types: could it be a new reliable tumor marker?

Massimo Papale

Discussion

YY1 in bone homeostasis and tumor angiogenesis

Filomena De Nigris

YY1 as a moderator of stress-induced resistance of colorectal cancer cells to immune-mediated cytotoxicity

Stavroula Baritaki

YY1 regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells

Kathy Lui

Discussion

Closing remarks

City tour – traditional Cypriot food dinner

GSK3 and RKIP in metabolic disorders: A proposal for a joint international research program

Fahd Al-Mulla

RKIP protects mitochondria under ischemic conditions

Theresa Brand

To be confirmed: Presenter not on the invited speaker list.

Characterization of RKIP expression in different histological variants of leiomyoma and in leiomyosarcoma

Pasquapina Ciarmela

RKIP/PEBP1: Central to the Redox Loxsisome, Epithelial Biology and Asthma

Sally Wenzel

Effect of PHB ligands on RKIP expression and phosphorylation

Laurent Désaubry

To be confirmed: Presenter not on the invited speaker list.

Discussion

Coffee break / poster session

Different Role of Yin Yang 1 in Colon Cancer and B-cell NHL cells

Silvia Vivarelli

Understanding the role of YY1 and YAP in neurofibromatosis type 2 (NF2)

Joseph Kissil

Reprogramming effect of preimplantation embryonic microenvironment on cancer stem cells and the role of Yin Yang 1

Gulperi Oktem

To be confirmed: Time conflict: two talks are listed at 11:55 am.

Yin Yang 1 Phosphorylation Induces Vascular Endothelial Proliferation Promoting Atherosclerosis Under Disturbed Flow

Jeng-Jiann Chiu

To be confirmed: Time conflict: two talks are listed at 11:55 am.

Discussion

To be confirmed: Brief lists this time as “12:35 am”.

Light lunch

RKIP and Lung Cancer: from the bench to bedside

Olga Martinho

Therapeutic effect of a novel chemical inhibitor of RKIP and TβR1 binding on NF2 syndrome

Bum-Joon Park

The role of RKIP in inflammation and tumor immunity

Xiaojian Wang (Hangzhou)

To be confirmed: Presenter not on the invited speaker list.

A stochastic binary model for the regulation of gene expression to investigate responses to gene therapy

Alexandre Ramos

Discussion

Cross-talks between RKIP and YY1: A multilevel pan-cancer analysis focusing on their expression, mutation, methylation, immune infiltration, and drug resistance

Apostolos Zaravinos

RKIP and YY1 expression is modulated in tumour cells after repeated treatment with anticancer drugs inducing oxidative stress: implications for the development of tumour resistance

Valentina Rapozzi

RKIP downregulation is associated with YY1 overexpression in lung cancer: Diagnostic and Prognostic implication

Luca Falzone

Who is the winner? RKIP (David) or YY1 (Goliath) in fighting cancer

Benjamin Bonavida

Discussion

Closing remarks

Arman Lari

To be confirmed: Speaker not on the committee or invited speaker list.

Social dinner